The Bucksport fire department says the call came in just after two o’clock Tuesday afternoon.
When crews arrived at the home at 44 Middle Street, most people had already vacated the building, but firefighters did have to rescue a few others.
Four units in the apartment house were damaged, three of those from smoke.
Firefighters say the blaze started in the kitchen of one of the apartments.
A couple of people were treated at the scene for smoke inhalation and stress.